Faculty of the Division of Biostatistics are engaged in a wide variety of methodological research. Major areas of research include: Bayesian modeling, Biomedical image analysis, Causal inference, Clinical trials, Functional data analysis, Health economics, Joint modeling, Longitudinal methods, Missing data, Nonparametric and high-dimensional statistics, Prognostic models, Spatial analyses, Survey sampling, Statistical genetics/genomics, and Survival analysis.

Areas of application include: Aging, Bioinformatics, Cancer, Cardiology, Clinical epidemiology, Clinical trials, Comparative effectiveness research, Disparities research, Health services, Infectious diseases, HIV/AIDS, Medical imaging, Mental/behavioral health, Neurology/Neurodegenerative diseases, Obesity, Pharmacoepidemiology, Pediatrics/Neonatology, Psychiatry/Psychometrics, Genetics/Genomics, Translational sciences, Urology/renal diseases, Wearable computing sensors/accelerometry, and Women’s health

**Methodological Research Tools led by Biostatistics faculty include:**

Please contact Martin Das, if you would like to list your newly developed tools.

**Current Methodological Research grants led by Biostatistics faculty include:**

**Title** |
**Faculty Name** |
**Role** |

Semi-Parametric Subgroup Analysis For Longitudinal Data With Applications To Multidisciplinary Approach To The Study Of Chronic Pelvic Pain (Mapp) Study |
Wensheng Guo, PhD |
PI |

Single-Cell Transcriptomic Analysis Of Human Retina |
Mingyao Li, PhD |
PI |

Improving Confounder Control In EHR-Based Studies Of Cancer Epidemiology |
Rebecca Hubbard, PhD |
PI |

Statistical Methods In MHealth To Signal Interventional Needs For Mental Health Patients |
Ian J. Barnett, PhD |
PI |

Advancing Analysis Of Multi-Omics Data In Alzheimer's Disease Research |
Qi Long, PhD |
PI |

Limited Competition For Continuation Of The MAPP-RN DCC |
J. Richard Landis, PhD |
PI |

Statistical Methods For Microbiome And Metagenomics |
Hongzhe Lee, PhD |
PI |

Methods For Integrative Genomic Data Analysis |
Hongzhe Lee, PhD |
PI |

Statistical Methods For Analyzing Electronic Health Record Data |
Jinb Chen, PhD |
PI |

Biostatistics For Renal And Urologic Diseases |
Justine Shults, PhD |
PI |

Statistical Methods For Single-Cell Transcriptomics |
Mingyao Li, PhD |
PI |

Nancy Zhang, PhD |
Site PI |

A General Framework To Account For Outcome Reporting Bias In Systematic Reviews |
Yong Chen, PhD |
PI |

Mental Health Biostatistics Training Grant |
Warren B. Bilker, PhD |
PI |

Statistical Methods For Transcriptome Profiling Using RNA Sequencing |
Mingyao Li, PhD |
PI |

Dynamic learning for post-vaccine event prediction using temporal information in VAERS |
Yong Chen, PhD |
MPI |

Cui Tao, PhD (U. Texas) |
MPI |

Statistical Methods for Phenotype Estimation and Analysis Using Electronic Health Records |
Rebecca Hubbard, PhD |
PI |

Methods for Genomic Data with Graphical Structures |
Hongzhe Li, PhD |
PI |

Development and assessment of decision supporting system for renal studies |
Amita Manatunga (Emory) |
PI |

Qi Long, PhD |
Site PI |

Statistical Methods for Large and Complex Databases of Ultra High Dimensional Imaging |
Russell Taki Shinohara, PhD |
PI |

**Completed Methodological Research Awards led by Biostatistics faculty include:**

**Title** |
**Faculty Name** |
**Role** |

Statistical Methods for Cancer Absolute Risk Prediction |
Jinbo Chen, PhD |
PI |

Statistical Methods and Software for Multivariate Meta-analysis |
Haitao Chu, PhD (U. Minnesota) |
PI |

Yong Chen, PhD |
Site PI |

Semi-parametric Joint Models for Longitudinal and Time to Event Data |
Wensheng Guo, PhD |
MPI |

Sarah Ratcliffe, PhD |
MPI |

Statistical Methods for Transcriptome Profiling using RNA-Sequencing |
Mingyao Li, PhD |
PI |

Elucidation of Tissue-Specific Transcriptomic Profiles in Cardiometabolic Disease |
Muredach Reilly, MBBCH, MSCE |
MPI |

Mingyao Li, PhD |
MPI |

Statistical Methods for Causal Inference in Observational Studies |
Qi Long, PhD |
PI |

Statistical Methods for Missing Data in Large Observational Studies |
Qi Long, PhD |
PI |

Non-Parametric Bayesian Methods for Causal Inference |
Jason Roy, PhD |
PI |

Spatiotemporal Modeling of MRI Grain Lesion Trajectories of Biomarker Discovery |
Russell Taki Shinohara, PhD |
PI |

A Partially Linear Tree-Based Regression Model for Assessing Complex Joint Gene-G |
Jinbo Chen, PhD |
PI |

Statistical Methods in Genetic Epidemiology Research |
Jinbo Chen, PhD |
PI |

Genome-Wide Association Studies Using Integrated CNV and SNP Information |
Rui Feng, PhD |
PI |

New Functional Models for Biomedical Data |
Wensheng Guo, PhD |
PI |

Automatic Statistical Time-Frequency Analysis |
Wensheng Guo, PhD |
PI |

Statistical Methods in Smoking Cessation Research |
Daniel Heitjan, PhD |
PI |

Statistical Methods for Estimation of Benefits & Harms of Repeat Cancer Screening |
Rebecca Hubbard, PhD |
PI |

Analysis of Case-Control Follow-Up Studies |
Marshall Joffe, MD, MPH, PhD |
PI |

Estimating Causal Effects in Longitudinal Studies |
Marshall Joffe, MD, MPH, PhD |
PI |

Causal Methods for Mediation and Interaction |
Marshall Joffe, MD, MPH, PhD |
PI |

Instrumental Variable Methods for Longitudinal Discrete Data |
Marshall Joffe, MD, MPH, PhD |
PI |

Selective and Future Ignorability in Causal Inference |
Marshall Joffe, MD, MPH, PhD |
PI |

Joint Analysis of Longitudinal Outcomes & Clinical Events in Kidney Disease |
Tom Greene, PhD (U. Utah) |
MPI |

Marshall Joffe, MD, MPH, PhD |
MPI |

Liang Li, PhD (Cleveland Clinic) |
MPI |

Statistical Methods for Next-Generation Sequence Data |
Hongzhe Li, PhD |
PI |

Survival Models for Mapping Genes for Complex Diseases |
Hongzhe Li, PhD |
PI |

Statistical Methods for Gene Mapping Studies in Admixed Populations |
Mingyao Li, PhD |
PI |

Developing Statistical Methods For Disease Gene Discovery |
Chun Li, PhD (Vanderbilt U.) |
MPI |

Mingyao Li, PhD |
MPI |

Clinical Meaningful Measures from Complex Designs |
Russell Localio, JD, MA, MPH, MS, PhD |
PI |

Applied Methods for Analysis of Interstitial Cystitis |
Kathleen Propert, ScD |
PI |

Longitudinal Analysis for Diverse Populations Project |
Justine Shults, PhD |
PI |

Causal Methods for Mediation and Interaction |
Thomas Ten Have, PhD |
PI |

Mixed Effects Models - Discrete Data with Non-Compliance |
Thomas Ten Have, PhD |
PI |